Applications of nanodiamonds in medical and sensor fields

JIANG Lin; WANG Chengyong; ZHANG Yue; GUO Ziying

doi:10.13394/j.cnki.jgszz.2024.0028

Volume 45 Issue 3

Jun. 2025

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JIANG Lin, WANG Chengyong, ZHANG Yue, GUO Ziying. Applications of nanodiamonds in medical and sensor fields[J]. Diamond & Abrasives Engineering, 2025, 45(3): 300-315. doi: 10.13394/j.cnki.jgszz.2024.0028

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JIANG Lin, WANG Chengyong, ZHANG Yue, GUO Ziying. Applications of nanodiamonds in medical and sensor fields[J]. Diamond & Abrasives Engineering, 2025, 45(3): 300-315. doi: 10.13394/j.cnki.jgszz.2024.0028

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Applications of nanodiamonds in medical and sensor fields

doi: 10.13394/j.cnki.jgszz.2024.0028

JIANG Lin^{1, 2, 3},
WANG Chengyong^{1, 2, 3
,
,},
ZHANG Yue^{1, 2, 3},
GUO Ziying^{1, 2, 3}

1.
College of Mechanical and Electrical Engineering, Guangdong University of Technology, Guangzhou 510006, China
2.
State Key Laboratory for High performance Tools, Guangzhou 510006, China
3.
Guangdong Provincial Key Laboratory of Minimally Invasive Surgical Instruments and Manufacturing Technology, Guangzhou 510006, China

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Received Date: 2024-02-08
Accepted Date: 2024-04-23
Rev Recd Date: 2024-04-10

Abstract

Abstract

Significance This study systematically reviews the applications of nanodiamonds in the medical and sensor industries, along with their fabrication techniques and inherent properties. Nanodiamonds, characterized by their unique physicochemical attributes, such as high hardness, favorable biocompatibility, optical characteristics, and electrical properties, are posited to hold substantial promise for diverse applications in these domains. Progress The article delineates a variety of synthesis methods for nanodiamonds, encompassing detonation synthesis, chemical vapor deposition, ball milling, high-temperature high-pressure synthesis, and laser ablation. It also presents an analytical review of the advantages and disadvantages inherent to each technique. Furthermore, the study addresses advancements in nanodiamond surface modification, biocompatibility, and electrical and optical properties. It concludes with a comprehensive summary of nanodiamond applications in the medical and sensor fields, highlighting their utilization in biological labeling and imaging, anti-infective therapy, tissue engineering and repair, cancer treatment, biosensors, electrochemical and gas sensors, and pressure sensors, among others. Conclusions and Prospects The article acknowledges the broad application prospects of nanodiamonds in the medical and sensor sectors, while also highlighting existing research gaps, such as the need for improved purity, yield, and size uniformity during synthesis, challenges in achieving efficient and controllable fluorescence for imaging, and an incomplete understanding of nanodiamonds' metabolic pathways and biological impact within living organisms. The article also speculates on potential future directions for nanodiamond research, including enhancing synthesis quality, achieving precise control over fluorescence properties, elucidating their metabolic pathways and biological effects, and developing more efficient and sensitive biosensors. This review article offers a comprehensive research perspective on the applications of nanodiamonds in the medical and sensor fields, and presents constructive suggestions for future research directions.
- nanodiamonds,
- performance,
- medical treatment,
- sensor

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References(79)

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